AORTA Gene: Polygenic prediction improves detection of thoracic aortic aneurysm
Preprint 2023 en
Authors
JP
James P. Pirruccello
SK
Shaan Khurshid
HL
Honghuang Lin
Abstract
1 min read
Genetic information improved estimation of thoracic aortic diameter when added to clinical risk factors. Larger and more diverse cohorts will be needed to develop more powerful and equitable scores.
James P. Pirruccello, Shaan Khurshid, Honghuang Lin, Lu-Chen Weng, Siavash Zamirpour, Shinwan Kany, Avanthi Raghavan, Satoshi Koyama, Ramachandran S. Vasan, Emelia Benjamin, Mark E. Lindsay, Patrick T. Ellinor
James P. Pirruccello, Mark Chaffin, Stephen J. Fleming, Alessandro Arduini, Honghuang Lin, Shaan Khurshid, Elizabeth L. Chou, Sam Friedman, Alexander G. Bick, Lu‐Chen Weng, Seung Hoan Choi, Amer-Denis Akkad, Puneet Batra, Nathan R. Tucker, Amelia Weber Hall, Carolina Roselli, Emelia Benjamin, Shamsudheen Karuthedath Vellarikkal, Rajat M. Gupta, Christian M. Stegman, Jennifer E. Ho, Udo Hoffmann, Steven A. Lubitz, Anthony Philippakis, Mark E. Lindsay, Patrick T. Ellinor
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