Antiviral Activity of Selected Nucleoside Analogues Against Human Herpes Virus Type 6

D. Reymen; Lieve Naesens; Jan Balzarini; Antonı́n Holý; De Clercq Erik

doi:10.1080/15257779508012429

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Antiviral Activity of Selected Nucleoside Analogues Against Human Herpes Virus Type 6

Article 1995 en

Abstract

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Abstract HHV-6 was evaluated in vitro for its susceptibility to a broad range of nucleoside analogues. PFA and several acyclic nucleoside phophonates emerged as the most potent inhibitors of HHV-6 replication as monitored by a newly developed immunofluorescence / flow cytometric assay as well as by microscopical evaluation of their inhibitory effect on HHV-6-induced cytopathogenicity.

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