Antimicrobial Photodynamic Therapy with Decacationic Monoadducts and Bisadducts of [70]Fullerene: In Vitro and In Vivo Studies

Liyi Huang; Min Wang; Tianhong Dai; Felipe Fornias Sperandio; Ying‐Ying Huang; Xuan Yi; Long Y. Chiang; Michael R Hamblin

doi:10.2217/nnm.13.22

Back

Antimicrobial Photodynamic Therapy with Decacationic Monoadducts and Bisadducts of [70]Fullerene: In Vitro and In Vivo Studies

Article 2013 en

Abstract

1 min read

We propose that the attachment of an additional deca(tertiary-ethylenylamino)malonate arm to C70 allowed the moiety to act as a potent electron donor and increased the generation yield of hydroxyl radicals under UVA illumination.

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Article2013

Synthesis of Decacationic C70 Bisadducts by Incorporating Covalently BoundElectron-Donors for Enhancement of Radical-Based Type-I PDT

Min Wang, Liyi Huang, Tianhong Dai, Felipe Fornias Sperandio, Ying‐Ying Huang, Michael R Hamblin, Long Y. Chiang

Article2015

Potentiation of Antimicrobial Photodynamic Inactivation Mediated by a Cationic Fullerene by Added Iodide: In Vitro and in Vivo Studies

Yunsong Zhang, Tianhong Dai, Min Wang, Daniela Vecchio, Long Y. Chiang, Michael R Hamblin

Article2018

Antimicrobial Photodynamic Inactivation Mediated by Tetracyclines in Vitro and in Vivo: Photochemical Mechanisms and Potentiation by Potassium Iodide

Weijun Xuan, Ya He, Liyi Huang, Ying‐Ying Huang, Brijesh Bhayana, Liyan Xi, Jeffrey A. Gelfand, Michael R Hamblin

Article2018

Inorganic Salts and Antimicrobial Photodynamic Therapy: Mechanistic Conundrums?

Michael R Hamblin, Heidi Abrahamse

Article2015

Photodynamic Therapy with Hexa(sulfo-n-butyl)[60]Fullerene Against Sarcoma In Vitro and In Vivo

Chi Yu, Pinar Avci, Taizoon Canteenwala, Long Y. Chiang, Bao‐Ji Chen, Michael R Hamblin

Antimicrobial Photodynamic Therapy with Decacationic Monoadducts and Bisadducts of [70]Fullerene: <i>In Vitro</i> and <i>In Vivo</i> Studies

Abstract

Discussion(0)

Related publications

Synthesis of Decacationic C<sub>70</sub> Bisadducts by Incorporating Covalently BoundElectron-Donors for Enhancement of Radical-Based Type-I PDT

Potentiation of Antimicrobial Photodynamic Inactivation Mediated by a Cationic Fullerene by Added Iodide: <i>In Vitro</i> and <i>in Vivo</i> Studies

Antimicrobial Photodynamic Inactivation Mediated by Tetracyclines in Vitro and in Vivo: Photochemical Mechanisms and Potentiation by Potassium Iodide

Inorganic Salts and Antimicrobial Photodynamic Therapy: Mechanistic Conundrums?

Photodynamic Therapy with Hexa(sulfo-<i>n</i>-butyl)[60]Fullerene Against Sarcoma <i>In Vitro</i> and <i>In Vivo</i>