Anti-HIV Activity of Thiosemicarbazone and Semicarbazone Derivatives of (±)-3-Menthone

Vibha Mishra; S. N. Pandeya; Christophe Pannecouque; Myriam Witvrouw; De Clercq Erik

doi:10.1002/1521-4184(200205)335:5<183::aid-ardp183>3.0.co;2-u

Back

Anti-HIV Activity of Thiosemicarbazone and Semicarbazone Derivatives of (±)-3-Menthone

Article 2002 en

Abstract

1 min read

A series of thiosemicarbazones and semicarbazone derivatives of (+/-)-3-menthone have been synthesized and their anti-HIV activity evaluated against HIV-1(III(B))and HIV-2 (ROD). The studies revealed that maximum protection is offered by chloro-substituted derivatives 2 and 7 against HIV-1 (III(B)) and HIV-2 (ROD).

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Article2001

Synthesis and anti-HIV activity of some isatin derivatives.

Sridhar Sk, Pandeya Sn, De Clercq Erik

Article2013

Synthesis of some novel thiosemicarbazone derivatives having anti-cancer, anti-HIV as well as anti-bacterial activity

Hitesh D. Patel, Saavani Malove Divatia, De Clercq Erik

Article2013

Design, synthesis, antimicrobial activity and anti-HIV activity evaluation of novel hybrid quinazoline–triazine derivatives

Rahul P. Modh, De Clercq Erik, Christophe Pannecouque, Kishor H. Chikhalia

Article2009

Synthesis and Studies of New 2‐(Coumarin‐4‐yloxy)‐4,6‐(substituted)‐s‐Triazine Derivatives as Potential Anti‐HIV Agents

Dharmesh H. Mahajan, Christophe Pannecouque, De Clercq Erik, Kishor H. Chikhalia

Article2013

Design, Synthesis and Biological Evaluation of Substituted Guanidine Indole Derivatives as Potential Inhibitors of HIV-1 Tat-TAR Interaction

Jun Wang, Yan Wang, Zhenyu Li, Peng Zhan, Ru-Jun Bai, Christophe Pannecouque, Jan Balzarini, De Clercq Erik, Xinyong Liu