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doi:10.1038/nrmicro3569

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Evolution and classification of the CRISPR–Cas systems

Kira S. Makarova, Daniel H. Haft, Rodolphe Barrangou, Stan J. J. Brouns, Emmanuelle Charpentier, Philippe Horvath, Sylvain Moineau, Francisco J. M. Mojica, Yuri I. Wolf, Alexander F. Yakunin, John van der Oost, Eugene V Koonin

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