Agreement between different input image types in brain atrophy measurement in multiple sclerosis using SIENAX and SIENA

Veronica Neacsu; Bas Jasperse; Tijmen Korteweg; Dirk L. Knol; Paola Valsasina; Massimo Filippi; Frederik Barkhof; Marco Rovaris; Hugo Vrenken

doi:10.1002/jmri.21501

Abstract

1 min read

Brain atrophy can be studied using SIENA and SIENAX if T1-weighted images without contrast agent are not available. T1-weighted images with contrast agent should be used if available. Otherwise, pseudo-T1 and T2-weighted images seem acceptable and accessible alternatives. The use of these other images will greatly improve research possibilities, especially regarding older datasets.

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