Aggregation-induced emission photosensitizer for antibacterial therapy of methicillin-resistant <i>Staphylococcus aureus</i>

A cationic AIE-PS, MNNPyBB damages membrane/wall of methicillin-resistant bacteria. Wound closure was achieved with normal re-epithelialization and preserved skin morphology. This study facilitates the structural regulation, performance modulation of broad-spectrum antibiotics.