Age at Natural Menopause and Risk of Cardiovascular Disease

Frank B Hu; Francine Grodstein; Charles H. Hennekens; Graham A. Colditz; Michelle Johnson; JoAnn E. Manson; B. A. Rosner; Meir J. Stampfer

doi:10.1001/archinte.159.10.1061

Abstract

1 min read

We observed an overall significant association between younger age at menopause and higher risk of CHD among women who experienced natural menopause and never used hormone therapy. This increased risk was observed among current smokers but not among never smokers. The apparent elevated risk of CHD with decreased age at natural menopause among smokers might reflect residual confounding by smoking.

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