Additional file 1 of Adiposity, metabolites, and colorectal cancer risk: Mendelian randomization study
Dataset en
Authors
CB
Caroline J. Bull
JB
Joshua A. Bell
NM
Neil Murphy
Abstract
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Additional file 1: Table S1. Genetic variants used to instrument BMI, WHR and metabolites. Table S2. Assesment of instrument strength. Table S3. Colorectal cancer case distributions by study, sex and site. Table S4. LogOR colorectal cancer per SD higher BMI or WHR. Table S5. Beta change in NMR-detected metabolite per SD higher BMI or WHR. Table S6. LogOR colorectal cancer per SD higher BMI or WHR-driven NMR-detected metabolite. Table S7. Risk of overall colorectal cancer per SD higher adipose or metabolite trait, estimated using multivariable Mendelian randomization. Table S8. Posthoc investigations.
Caroline J. Bull, Joshua A. Bell, Neil Murphy, Eleanor Sanderson, George Davey Smith, Nicholas J. Timpson, Barbara L. Banbury, Demetrius Albanes, Sonja I. Berndt, Stéphane Bezieau, D. Timothy Bishop, Hermann Brenner, Daniel D. Buchanan, Andrea N. Burnett‐Hartman, Graham Casey, Sergi Castellví–Bel, Andrew T. Chan, Jenny Chang‐Claude, Amanda J. Cross, Albert de la Chapelle, Jane C. Figueiredo, Steven Gallinger, Sue M. Gapstur, Graham G. Giles, Stephen B. Gruber, Andrea Gsur, Jochen Hampe, Heather Hampel, Tabitha A. Harrison, Michael Hoffmeister, Li Hsu, Wen‐Yi Huang, Jeroen R. Huyghe, Mark A. Jenkins, Corinne E. Joshu, Temitope O. Keku, Tilman Kühn, Sun‐Seog Kweon, Loı̈c Le Marchand, Christopher I. Li, Li Li, Annika Lindblom, Vicente Martín, Anne M. May, Roger L. Milne, Vı́ctor Moreno, Polly A. Newcomb, Kenneth Offit, Shuji Ogino, Amanda I. Phipps, Elizabeth A. Platz, John D. Potter, Conghui Qu, J. Ramón Quirós, Gad Rennert, Elio Riboli, Lori C. Sakoda, Clemens Schafmayer, Robert E. Schoen, Martha L. Slattery, Catherine M. Tangen, Konstantinos K. Tsilidis, Cornelia M. Ulrich, Fränzel JB van Duijnhoven, Bethany Van Guelpen, Kala Visvanathan, Pavel Vodička, Ludmila Vodičková, Hansong Wang, Emily White, Alicja Wolk, Michael O. Woods, Anna H. Wu, Peter T. Campbell, Wei Zheng, Ulrike Peters, Emma E. Vincent, Marc J. Gunter
Nils Thieme, Vincent W. Wu, Axel Dietschmann, Asaf Salamov, Mei Wang, Jenifer Johnson, Vasanth Singan, Igor V. Grigoriev, N. Glass, Chris Somerville, J. Benz
Caroline J. Bull, Joshua A. Bell, Neil Murphy, Eleanor Sanderson, George Davey Smith, Nicholas J. Timpson, Barbara L. Banbury, Demetrius Albanes, Sonja I. Berndt, Stéphane Bezieau, D. Timothy Bishop, Hermann Brenner, Daniel D. Buchanan, Andrea N. Burnett‐Hartman, Graham Casey, Sergi Castellví–Bel, Andrew T. Chan, Jenny Chang‐Claude, Amanda J. Cross, Albert de la Chapelle, Jane C. Figueiredo, Steven Gallinger, Susan M. Gapstur, Graham G. Giles,
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