Activity of the Anti-Orthopoxvirus Compound ST-246 against Vaccinia, Cowpox and Camelpox Viruses in Cell Monolayers and Organotypic Raft Cultures

Sophie Duraffour; Robert Snoeck; Rita De Vos; Joost J. van den Oord; Jean‐Marc Crance; Daniel Garín; Dennis E. Hruby; Robert Jordan; De Clercq Erik; Graciela Andreï

doi:10.1177/135965350701200802

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Activity of the Anti-Orthopoxvirus Compound ST-246 against Vaccinia, Cowpox and Camelpox Viruses in Cell Monolayers and Organotypic Raft Cultures

Article 2007 en

Abstract

1 min read

These data indicate that ST-246 is a potent anti-orthopoxvirus compound; the mode of inhibition is dependent on the virus and cell type.

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Activity of the Anti-Orthopoxvirus Compound ST-246 against Vaccinia, Cowpox and Camelpox Viruses in Cell Monolayers and Organotypic Raft Cultures

Abstract

Discussion(0)

Related publications

An Orally Bioavailable Antipoxvirus Compound (ST-246) Inhibits Extracellular Virus Formation and Protects Mice from Lethal Orthopoxvirus Challenge

Efficacy of 2-Amino-7-(1,3-Dihydroxy-2-Propoxymethyl)Purine for Treatment of Vaccinia Virus (Orthopoxvirus) Infections in Mice

Camelpox virus encodes a schlafen-like protein that affects orthopoxvirus virulence

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Organotypic Epithelial Raft Cultures as a Model for Evaluating Compounds against Alphaherpesviruses