Activation of latent TGF-β1 within the hepatocyte contributes to connective tissue growth factor (CTGF/CCN2) expression via entirely intracellular signalling — OA Gressner (2008) | RDL Network
Activation of latent TGF-β1 within the hepatocyte contributes to connective tissue growth factor (CTGF/CCN2) expression via entirely intracellular signalling
Article 2008 en
Authors
OG
OA Gressner
BL
Birgit Lahme
KR
Katharina Rehbein
Abstract
1 min read
Introduction: TGF-β is regarded as the profibrogenic master cytokine. We aimed at analyzing the regulatory link between TGF-b dependent CTGF-induction and intracellular demasking of latent TGF-b in hepatocytes (PC) of healthy and injured livers.
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