Across 73 meta-analyses mortality improvements are uncommon with newer interventions in adult cardiac surgery

Austin J. Parish; George Tolis; John P A Ioannidis

doi:10.1016/j.jclinepi.2025.111764

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Across 73 meta-analyses mortality improvements are uncommon with newer interventions in adult cardiac surgery

Article 2025 en

Abstract

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The vast majority of newer interventions had no mortality differences over older ones both overall and specifically in RCTs, while benefits for newer interventions were reported more frequently in observational studies.

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