Abnormalities of Resting State Functional Connectivity Are Related to Sustained Attention Deficits in MS

Marisa Loitfelder; Massimo Filippi; Maria A. Rocca; Paola Valsasina; Stefan Ropele; Margit Jehna; Siegrid Fuchs; Reinhold Schmidt; Christa Neuper; Franz Fazekas; Christian Enzinger

doi:10.1371/journal.pone.0042862

Abstract

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We provide evidence for adaptive changes in RS-FC in MS patients compared to HC in a sustained attention network. These results extend and partly mirror findings of task-related fMRI, suggesting FC may increase our understanding of cognitive dysfunction in MS.

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Abnormalities of Resting State Functional Connectivity Are Related to Sustained Attention Deficits in MS

Abstract

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