A preliminary study on clinical significance and method of using carbon nanoparticles in endoscopic treatment of papillary thyroid microcarcinoma

Objective To explore the value and method of using carbon nanoparticles in endoscopic treatment of papillary thyroid microcarcinoma. Method 74 cases were randomly divided into two groups, 34 cases in experimental group which were injected with carbon nanoparticles, and 40 cases in the control group without any injection. All cases were analyzed in terms of the tumor size, the number of lymph nodes and parathyroid gland injury. Results All patients underwent the operation smoothly. The postoperative pathological specimens result showed there was no statistical difference of carcinoma size between the two groups. The number of lymph nodes dissected was 177 in the control group and 220 in the experimental group (the rate of lymph node black staining rate was 89%) . In the experimental group, the average number of lymph node detected in each patient was 6.47±2.13, more than 4.42±1.91 in the control group. The number of parathyroid glands found in the experimental group was 3 and 11 in the control group, and the difference had no statistical significance. Postoperative temporary laryngeal recurrent nerve injury occurred to 2 cases in each group, and no statistical difference was found. Conclusion Using carbon nanoparticles in endoscopic treatment of papillary thyroid microcarcinoma can increase the detection rate of lymph node, and to some extent, reduce the parathyroid injury. It has a certain clinical significance, However, care should be taken to avoid contamination of the mirror field of view. Key words: Endoscopy; Papillary thyroid microcarcinoma; Carbon nanoparticles; Lymph node; Parathyroid gland