The likelihood of restenosis is a major limitation of coronary angioplasty. We studied whether hirudin, a highly selective inhibitor of thrombin with irreversible effects, would prevent restenosis after angioplasty. We compared two regimens of recombinant hirudin with heparin.
Arjan A. van den Bos, Jaap W. Deckers, Guy R. Heyndrickx, GertJan Laarman, Harry Suryapranata, Felix Zijlstra, Philippe Close, J. J. M. M. Rijnierse, H. R. Büller, Patrick W. Serruys
Vitali Verin, Youri Popowski, Bernard De Bruyne, Dietrich Baumgart, W. Sauerwein, Markus Lins, György Kovács, Martyn Thomas, F. Calman, Clemens Disco, Patrick W. Serruys, William Wijns, Marleen Piessens, John M. Kurtz, Ruediger Simon, Patrice Delafontaine, Raimund Erbel
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