A Case of Systemic Anaplastic Large Cell Lymphoma with Secondary Cutaneous Involvement
Article 2023 en
Authors
AB
Andie Bulbin
SS
Sarah Stano
KK
Kalliope Kyriakides
Abstract
1 min read
Systemic anaplastic large cell lymphoma (sALCL) is a rare, malignant T-cell lymphoma characterized by CD30 expression. There are two subtypes: ALK-positive sALCL and ALK-negative sALCL. In either condition, extranodal involvement is uncommon. We report a unique case in a 75-year-old woman who presented with multiple crops of occasionally pruritic papules in different stages of healing along her back for 3-4 weeks. The patient also showed erythematous papules on her arms, as well as lymphadenopathy. After considering other cutaneous T-cell lymphomas, the ultimate diagnosis of ALK-negative sALCL was determined using the clinical data, results of punch biopsy, and immunohistochemical staining.
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