450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy — Bonnie R. Joubert (2012) | RDL Network
450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking during Pregnancy
Article 2012 en
Authors
BJ
Bonnie R. Joubert
SH
Siri E. Håberg
RN
Roy M. Nilsen
Abstract
1 min read
We identified a set of genes with methylation changes present at birth in children whose mothers smoked during pregnancy. This is the first study of differential methylation across the genome in relation to maternal smoking during pregnancy using the 450K platform. Our findings implicate epigenetic mechanisms in the pathogenesis of the adverse health outcomes associated with this important in utero exposure.
Wenche Nystad, Shyamal D. Peddada, Douglas A. Bell, Dan Joseph Stein, Michael C. Wu, Susan K. Murphy, Zhiqing Huang, Xuting Wang, Siri E. Håberg, Lea A. Cupul‐Uicab, Per Magne Ueland, Øivind Midttun, Stephanie J. London, Roy M. Nilsen, Bonnie R. Joubert, Cathrine Hoyo
Bonnie R. Joubert, Håberg Siri, Roy M. Nilsen, Dan Joseph Stein, Øivind Midttun, Per Magne Ueland, Michael C. Wu, Wenche Nystad, Shyamal Peddada, Stephanie J. London
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