4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)

Erden Banoğlu; Erşan Çelikoğlu; Susanna Völker; Abdurrahman Olğaç; Jana Gerstmeier; Ulrike Garscha; Burcu Çalışkan; Ulrich Sigmar Schubert; Andrea Carotti; Antonio Macchiarulo; Oliver Werz

doi:10.1016/j.ejmech.2016.02.027

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Ulrich Sigmar Schubert

4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)

Article 2016 en

Authors

EB
Erden Banoğlu
EÇ
Erşan Çelikoğlu
SV
Susanna Völker

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4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP)

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BRP-187: A potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase/5-lipoxygenase-activating protein (FLAP) complex assembly

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Substituted 5‐Benzyl‐2‐phenyl‐5H‐imidazo[4,5‐c]pyridines: A New Class of Pestivirus Inhibitors.

Substituted 5-benzyl-2-phenyl-5H-imidazo[4,5-c]pyridines: A new class of pestivirus inhibitors

Identification of multi-target inhibitors of leukotriene and prostaglandin E2 biosynthesis by structural tuning of the FLAP inhibitor BRP-7