3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer’s disease

Philip G. Haydon; David A. Bennett; Tracy L. Young‐Pearse; Gregory W. Carter; David Kaplan; Giuseppina Tesco; Selene Lomoio; Ravi S. Pandey; Nicolas Rouleau; Beatrice Menicacci; WonHee Kim; William Cantley

doi:10.1038/s41380-023-02147-3

Back

3D bioengineered neural tissue generated from patient-derived iPSCs mimics time-dependent phenotypes and transcriptional features of Alzheimer’s disease

Article 2023 en

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Preprint2022

3D bioengineered neural tissue generated from patient-derived iPSCs develops time-dependent phenotypes and transcriptional features of Alzheimer’s disease

Selene Lomoio, Ravi S. Pandey, Nicolas Rouleau, Beatrice Menicacci, WonHee Kim, William Cantley, Philip G. Haydon, David A. Bennett, Tracy L. Young‐Pearse, Gregory W. Carter, David Kaplan, Giuseppina Tesco

Article2022

Bioengineered models of Parkinson’s disease using patient-derived dopaminergic neurons exhibit distinct biological profiles in a 3D microenvironment

Nicholas J. Fiore, Yosif Ganat, Kapil Devkota, Rebecca Batorsky, Ming Lei, Kyongbum Lee, Lenore Cowen, Gist F. Croft, Scott Noggle, Thomas J.F. Nieland, David Kaplan

Article2019

3D bioengineered tissue model of the large intestine to study inflammatory bowel disease

Terrence T. Roh, Ying Chen, Harry T. Paul, Chengchen Guo, David Kaplan

Article2024

Repetitive injury causes Alzheimer’s disease‐like phenotypes via reactivation of HSV‐1 in a 3D human brain tissue model

Dana M. Cairns, Brooke M. Smiley, Jordan A. Smiley, Yasaman A Khorsandian, Marilyn Kelly, Ruth F. Itzhaki, David Kaplan

Article2020

P140 3D BIOENGINEERED TISSUE MODEL OF THE LARGE INTESTINE TO STUDY INFLAMMATORY BOWEL DISEASE

Terrence T. Roh, Ying Chen, Harry Paul, Chengchen Guo, David Kaplan