24-HOUR BLOOD PRESSURE MONITORING REGISTRY IN COLON CANCER PATIENTS

Objective: Colon cancer (CC) and cardiovascular (CV) diseases are highly coprevalent due to major risk factors common to both conditions. Hypertension is the most frequent comorbidity in oncologic patients with significant incidence of new onset hypertension associated with chemotherapy, leading to worse treatment effects and often being a trigger of related cardiotoxicity. Although blood pressure (BP) control should play an important role in the monitoring of oncologic therapy in patients with CC, available data shows that such patients are frequently overlooked compared to subjects without cancer and, consequently, BP targets are not achieved. Available studies on BP control in CC are very scarce, suffer from imperfect methodology and are limited only to traditional BP measurements. Design and method: On this background we started the registry aimed to gather the information about BP control and levels in newly diagnosed CC patients before and after starting anticancer therapy. In consecutive patients with new CC diagnosis 24-h BP monitoring and traditional BP measurements will be performed at the beginning and after 1 year of standard care. Additionally, clinical data including the type of oncologic therapy and echocardiographic data will be collected. Results: The increasing prevalence of CC diagnosis and improving long term survival imposes the need of adequate cardiovascular monitoring and prevention, including blood pressure assessment and management. At the moment the results of the just started registry are not yet available. Conclusions: In the future we expect that the collected data will provide evidence concerning hypertension prevalence in CC, out-of-office BP control and their correlations to oncologic treatment methods over one year observation. This may favour improved CV risk management in these patients.