2,3′-Anhydro-[l- (6′- O-benzoyl-2′,5′- dideoxy-β-D-glucofuranosyl)thymine], a Versatile Starting Material for Homo - Nucleosides

Johann Hiebl; Erich Zbiral; Jan Balzarinib; De Clercq Erik

doi:10.1080/07328319108046515

Back

2,3′-Anhydro-[l- (6′- O-benzoyl-2′,5′- dideoxy-β-D-glucofuranosyl)thymine], a Versatile Starting Material for Homo - Nucleosides

Article 1991 en

Abstract

1 min read

Abstract The synthesis of 2,3′- anhydro-[l- (6′-0 - benzoyl- 2′,5′- dideoxy-β-D-glucofuranosyl)thymine] 10, a versatile starting material for homo-2′, 3′- dideoxynucleosides is described. 10 is transformed to homo-AZT.

Discussion(0)

No comments yet. Be the first to comment.

Related publications

Article1992

Side-chain derivatives of biologically active nucleosides. Part 1. Side-chain analogs of 3'-azido-3'-deoxythymidine (AZT)

Johann Hiebl, Erich Zbiral, Jan Balzarini, De Clercq Erik

Article1996

Side-Chain Derivatives of Biologically Active Nucleosides. Part 2: Synthesis and anti-HIV Activity of 5′-C-Methyl Derivatives of 3′-Fluoro-3′-Deoxythymidine

Johann Hiebl, Erich Zbiral, Martin von Janta‐Lipinski, Jan Balzarini, De Clercq Erik

Article1991

Synthesis and Biological Properties of2-Amino-3-fluoro-2,3-Dideoxy-D-Pentofuranosides of Natural Heterocyclic Bases

Igor A. Mikhailopulo, Grigorii G. Sivets, Tamara I. Pricota, Nicolai E. Poopeiko, Jan Balzarini, De Clercq Erik

Article1995

Ein einfacher Weg zu <scp>D</scp>‐Apio‐β‐<scp>D</scp>‐furanosyl‐ und 2′‐Desoxyapio‐β‐<scp>D</scp>‐furanosylnucleosiden

Friedrich Hammerschmidt, Elisabeth Öhler, J.‐P. POLSTERER, Erich Zbiral, Jan Balzarini, De Clercq Erik

Article2000

Synthesis and Antitumor Activities of Novel Pyrimidine Derivatives of 2,3-O,O-Dibenzyl-6-deoxy-<scp>l</scp>-ascorbic Acid and 4,5-Didehydro-5,6- dideoxy-<scp>l</scp>-ascorbic Acid

Silvana Raić‐Malić, Draženka Svedružić, Tatjana Gazivoda, Andreja Marunović, Antonija Hergold‐Brundić, Ante Nagl, Jan Balzarini, De Clercq Erik, Mladen Mintas

2,3′-Anhydro-[l- (6′- O-benzoyl-2′,5′- dideoxy-β-D-glucofuranosyl)thymine], a Versatile Starting Material for Homo - Nucleosides

Abstract

Discussion(0)

Related publications

Side-chain derivatives of biologically active nucleosides. Part 1. Side-chain analogs of 3'-azido-3'-deoxythymidine (AZT)

Side-Chain Derivatives of Biologically Active Nucleosides. Part 2: Synthesis and anti-HIV Activity of 5′-C-Methyl Derivatives of 3′-Fluoro-3′-Deoxythymidine

Synthesis and Biological Properties of<i>2</i>-Amino-3-fluoro-2,3-Dideoxy-D-Pentofuranosides of Natural Heterocyclic Bases

Ein einfacher Weg zu <scp>D</scp>‐Apio‐β‐<scp>D</scp>‐furanosyl‐ und 2′‐Desoxyapio‐β‐<scp>D</scp>‐furanosylnucleosiden

Synthesis and Antitumor Activities of Novel Pyrimidine Derivatives of 2,3-<i>O</i>,<i>O</i>-Dibenzyl-6-deoxy-<scp>l</scp>-ascorbic Acid and 4,5-Didehydro-5,6- dideoxy-<scp>l</scp>-ascorbic Acid