2-((3,5-Dimethyl-1-phenyl-1H-pyrazol-4-yl)methylene)indane-

Abstract: The title compound 2-[(3,5-dimethyl-1-phenyl-1 H -pyrazol-4-yl)methylene]-indane-1,3-dione ( 3) was synthesized in high yield by reaction of 3,5-dimethyl-1-phenyl-pyrazole-4-carbaldehyde and indane-1,3-dione in ethanol in the presence of pyridine. The structure of this new compound was confirmed by elemental analysis, IR, 1 H NMR, 13 C NMR and GC-MS spectral analysis. Keywords: Knoevenagel condensation; indane-1,3-dione; pyridine Naturally occurring as well as synthetic pyrazole-containing heterocyclic compounds have great importance for their biological activities such as anti-bacterial [1], anti-inflammatory [2], anti-hypertensive [3], anti-cancer [4], and anti-amoebic activity [5]. Pyrazole-containing donor-acceptor chromophores are also applicable in materials fields for their properties such as non-linear optical (NLO), optical limiting [6], electrochemical sensing [7] and langmuir film [8]. Due to the wide application of pyrazoles we decided to synthesize a new pyrazole-containing donor-acceptor chromophore by Knoevenagel condensation in analogy to a previously published procedure [9].