ADVERTISEMENT RETURN TO ISSUEForum ArticleNEXTPreface for the Forum on Imaging and Sensing: Probing and Utilizing the Elements of Life for Studying and Improving Health and SocietyChristopher J. Chang*†‡§⊥∥ and Kenneth N. Raymond*†∥View Author Information† †Department of Chemistry, ‡Department of Molecular and Cell Biology, §Howard Hughes Medical Institute, and ⊥Helen Wills Neuroscience Institute, University of California, Berkeley, California 94720, United States∥ Chemical Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720, United States*E-mail: [email protected]*E-mail: [email protected]Cite this: Inorg. Chem. 2014, 53, 4, 1791–1793Publication Date (Web):February 7, 2014Publication History Received15 January 2014Published online7 February 2014Published inissue 17 February 2014https://pubs.acs.org/doi/10.1021/ic500099nhttps://doi.org/10.1021/ic500099nresearch-articleACS PublicationsCopyright © 2014 American Chemical SocietyRequest reuse permissionsArticle Views801Altmetric-Citations4LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Elements,Fluorescence,Fluorescence resonance energy transfer,Metals,Molecular imaging Get e-Alerts
Abstract Optically active cyclohexanones as well as a cycloheptanone are formed from the corresponding silyl enol ethers.
CRISPR-Cas gene editing tools have brought us to an era of synthetic biology that will change the world. Excitement over the breakthroughs these tools have enabled in biology and medicine is balanced, justifiably, by concern over how their applications might go wrong in open environments. We do not know how genomic processes (including regulatory and epigenetic processes), evolutionary change, ecosystem interactions, and other higher order processes will affect traits, fitness, and impacts of edited organisms in nature. However, anticipating the spread, change, and impacts of edited traits or organisms in heterogeneous, changing environments is particularly important with “gene drives on the horizon.” To anticipate how “synthetic threads” will affect the web of life on Earth, scientists must confront complex system interactions across many levels of biological organization. Currently, we lack plans, infrastructure, and funding for field science and scientists to track new synthetic organisms, with or without gene drives, as they move through open environments.
AbstractThe following sections are included:Monopoly vs. Efficiency Interpretations of the Multinational EnterpriseHost-Country ControlsDynamic ConsiderationsConclusionREFERENCES
The problem is simplified to a linear analysis of the two-dimensional vibration of coupled reservoir-dam systems, with the response of the dam being approximated by its deformations in the fundamental mode. Four cases are considered: dam alone (without reservoir); reservoir-dam system-interaction neglected; reservoir-dam system-interaction included; and reservoir-dam system-interaction included but water compressibility neglected. Expressions for the complex frequency response functions for the dam displacement and lateral hydrodynamic force in each of these four cases are presented. These results along with the Fast Fourier Transform algorithm are utilized to compute the time-history of responses of 28 reservoir-dam systems to Taft, CA, earthquake. It is concluded that: (1) the presence of the reservoir may increase the dam response significantly, and (2) the commonly used simpler analyses which neglect reservoir interaction or compressibility of water may result in significant error.