2,833 publications from this institution
The future of critical care medicine will be shaped not only by the evidence-validated foundations of science, but also by innovations based on unproven and, in many cases, untested concepts and thoughtful visions of scientists and clinicians familiar with the complex problems actually faced in clinical practice. Clinical investigations and trials often lag behind collective experience and impressions, in a well-intentioned and necessary quest to determine the fallacy or validity of ongoing practice. Progress made in this way can be painfully slow, and imperfect theory may prove difficult to challenge. On occasion, an innovative paradigm shift fostered by a novel approach can reorient the forces of academic investigation toward generating an evidence base upon which such concepts and interpretations can find scientific justification. This discussion presents a selected set of ideas to improve the future practice of critical care - each having a defensible rationale, but unconfirmed validity.
From the currently available published data, it is difficult to determine whether there is a relationship between the age of transfused RBCs and outcome in adult patients, except possibly in trauma patients receiving massive transfusion.
Intravenous sivelestat had no effect on 28-day all-cause mortality or ventilator-free days in a heterogeneous acute lung injury patient population managed with low tidal volume mechanical ventilation.
info:eu-repo/semantics/published
Seit einigen Jahren gilt in vielen Gebieten der Medizin eine restriktive Transfusionsstrategie, nachdem eine Reihe von Publikationen gezeigt hat, dass unerwünschte Wirkungen einer Transfusion oft deren Nutzen überschreiten. Möglicherweise gilt das aber nicht grundsätzlich – eine Arbeitsgruppe aus Sao Paulo hat eine frühere Studie jetzt sekundär daraufhin ausgewertet.
Depuis 1949, dans la zone de St-Ségal, près de Châteaulin (Finistère), quatre enquêtes techniques, économiques et sociologiques ont porté, en 1949, 1960, 1969, 1984, sur toutes les exploitations de ce territoire de 3 000 ha (150 fermes en 1950, 64 en 1984). L'évolution technico-économique est très forte, à l'image de celle de la Bretagne agricole, et ceci surtout entre 1960 et 1974. Aujourd'hui, la diversité des systèmes de production et des types socio-économiques d'exploitation est considérable. Le tissu social agricole se désagrège. Les changements techniques (mécanisation, report de la main d'œuvre masculine vers l'élevage, ...) semblent n'induire des changements sociaux qu'avec un décalage important dans le temps.
The present research uncovers the dynamic nature of student discipline. The findings show that discipline escalates during the school year, that discipline escalates more severely for Black students, and that racial disparities in discipline ...Researchers have long used end-of-year discipline rates to identify punitive schools, explore sources of inequitable treatment, and evaluate interventions designed to stem both discipline and racial disparities in discipline. Yet, this approach leaves us ...
