Heterostructured metal−semiconductor Zn−ZnO core−shell nanobelts and nanotubes have been synthesized. The core is a belt-shaped Zn single crystal, and the shell is an epitaxially grown ZnO layer of ∼5 nm in thickness. The composite nanobelt grows along [21̄1̄0], its top/bottom being ±(0001), and side surfaces ±(011̄0). The Zn core is a single crystal, and the ZnO shell has an epitaxial orientation relationship with the core. The metal-based nanobelts have a distinct morphology from the nanowires reported in the literature. A growth mechanism is proposed on the basis of growth kinetics and thermodynamics. Sublimation of the Zn core results in the formation ZnO nanotubes.
We demonstrated a flexible strain sensor based on ZnSnO3 nanowires/microwires for the first time. High-resolution transmission electron microscopy indicates that the ZnSnO3belongs to a rhombohedral structure with an R3c space group and is grown along the [001] axis. On the
Objective To explore the value and method of using carbon nanoparticles in endoscopic treatment of papillary thyroid microcarcinoma. Method 74 cases were randomly divided into two groups, 34 cases in experimental group which were injected with carbon nanoparticles, and 40 cases in the control group without any injection. All cases were analyzed in terms of the tumor size, the number of lymph nodes and parathyroid gland injury. Results All patients underwent the operation smoothly. The postoperative pathological specimens result showed there was no statistical difference of carcinoma size between the two groups. The number of lymph nodes dissected was 177 in the control group and 220 in the experimental group (the rate of lymph node black staining rate was 89%) . In the experimental group, the average number of lymph node detected in each patient was 6.47±2.13, more than 4.42±1.91 in the control group. The number of parathyroid glands found in the experimental group was 3 and 11 in the control group, and the difference had no statistical significance. Postoperative temporary laryngeal recurrent nerve injury occurred to 2 cases in each group, and no statistical difference was found. Conclusion Using carbon nanoparticles in endoscopic treatment of papillary thyroid microcarcinoma can increase the detection rate of lymph node, and to some extent, reduce the parathyroid injury. It has a certain clinical significance, However, care should be taken to avoid contamination of the mirror field of view. Key words: Endoscopy; Papillary thyroid microcarcinoma; Carbon nanoparticles; Lymph node; Parathyroid gland
Male breast cancer (MBC) is a rare but aggressive malignancy with cellular and immunological characteristics that remain unclear. Here, we perform transcriptomic analysis for 111,038 single cells from tumor tissues of six MBC and thirteen female breast cancer (FBC) patients. We find that that MBC has significantly lower infiltration of T cells relative to FBC. Metastasis-related programs are more active in cancer cells from MBC. The activated fatty acid metabolism involved with FASN is related to cancer cell metastasis and low immune infiltration of MBC. T cells in MBC show activation of p38 MAPK and lipid oxidation pathways, indicating a dysfunctional state. In contrast, T cells in FBC exhibit higher expression of cytotoxic markers and immune activation pathways mediated by immune-modulatory cytokines. Moreover, we identify the inhibitory interactions between cancer cells and T cells in MBC. Our study provides important information for understanding the tumor immunology and metabolism of MBC.
Two new fields are introduced to the sensor community: strained induced piezotronics for smart CMOS and a nanogenerator that harvests mechanical energy for powering nanosystems. Fundamentally, due to the polarization of ions in a crystal that has non-central symmetry, such as ZnO, GaN and InN, a piezoelectric potential (piezopotential) is created in the crystal by applying a stress. We have replaced the externally applied gate voltage to a CMOS field effect transistor by the strain induced piezopotential as a "gate" voltage to tune/control the charge transport from source to drain. The devices fabricated by this principle are called piezotronics, with applications in strain/force/pressure triggered/controlled electronic devices, sensors and logic units. The principle of harvesting irregular mechanical energy by the nanogenerator relies on the piezopotenital driven transient flow of electrons in external load, which can be resulted from body motion, muscle stretching, breathing, tiny mechanical vibration/disturbance, sonic wave etc. As of today, a gentle straining can output 1-3 V at an instant output power of ∼2 μW from an integrated nanogenerator of a very thin sheet of 1 cm2 in size. This technology has the potential applications for power MEMS/NEMS that requires a power in the μW to mW range.